USMLE-Rx Step 1 Qmax Challenge #4091

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Check out today’s Step 1 Qmax Question Challenge.

Know the answer? Post it below! Don’t forget to check back for an update with the correct answer and explanation (we’ll post it in the comments section below).

USMLE-Rx Step 1 Qmax Challenge #4091A 70-year-old man complains of a long history of pain in his ankles, toes, and fingers. He has experienced intermittent acute attacks of exquisite pain every few months, followed by completely asymptomatic periods. In recent years, he has had near-constant discomfort at baseline, and now has permanent “swelling” in many of the joints of his fingers and toes. Joint fluid is aspirated, and the fluid is examined under polarized light (shown in the image). Treatment is initiated, and the patient’s uric acid levels gradually fall.

What is the mechanism of action of the best treatment?

A. Binds tubulin
B. Blocks formation of prostaglandins and thromboxane from arachidonic acid
C. Inhibits release of phospholipase A2
D. Inhibits xanthine oxidase
E. Selective, competitive angiotensin II receptor inhibition

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Mnemonic Monday: Back to Preschool!! Mnemonics for Pediatric Fine Motor Skills Milestones

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By Molly Lewis

In your Step 1 prep, you’ll most likely run across questions similar to this: “A mother brings her 4-year-old son into the pediatrician for a well-child visit. The boy is able to hop on one foot, has imaginary friends, can speak with prepositions, and can copy a circle. How is his development in terms of fine motor, gross motor, social, and verbal skills?

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Dear Future Doctor (Stanford School of Medicine Parody on “Dear Future Husband” by Meghan Trainor)

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We love this video from:
Stanford University School of Medicine

Got a video you would like us to feature? Let us know by emailing a link to submissions@usmle-rx.com

 

USMLE-Rx Step 1 Qmax Challenge #4065

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Check out today’s Step 1 Qmax Question Challenge.

Know the answer? Post it below! Don’t forget to check back for an update with the correct answer and explanation (we’ll post it in the comments section below).

USMLE-Rx Step 1 Qmax Challenge #4065The image depicts steps in an immunologic activation pathway.

This pathway is most important for which activity of the immune system?

A. Antibody production
B. Antigen presentation and destruction of intracellular pathogens
C. Defense against parasites by eosinophils
D. Immediate allergic hypersensitivity reaction
E. Neutrophil chemotaxis

———————–

Want to know the ‘bottom line?’ Purchase a USMLE-Rx Subscription and get many more features, more questions, and passages from First Aid, including images, references, and other facts relevant to this question.

This practice question is an actual question from the USMLE-Rx Step 1 test bank. For more USMLE Step 1 prep, subscribe to our Flash Facts and Step 1 Express video series. Score the best deal on all three products with a Step 1 Triple Play Bundle.

Mnemonic Monday: 7 Cute Ladies- Mnemonics for the Patient Interview

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By Molly Lewis

Whether you are a first year in Physical Diagnosis class, a second year in Continuity Clinic, a third year seeing consults, or an attending deciding if a patient needs emergency surgery, taking a complete history is a key aspect of patient care. How can you remember everything you need to ask? Try a mnemonic!

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USMLE-Rx Step 1 Qmax Challenge #4057

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Check out today’s Step 1 Qmax Question Challenge.

Know the answer? Post it below! Don’t forget to check back for an update with the correct answer and explanation (we’ll post it in the comments section below).

USMLE-Rx Step 1 Qmax Challenge #4057After a night of heavy drinking, a 37-year-old man experiences pain, warmth, swelling, and redness around his big toe, shown radiographically in the image. He had been previously warned against drinking heavily, as it could exacerbate the pain in his toe.

Which of the following enzymes is responsible for the final conversion of the product responsible for this patient’s pain?

A. Adenosine deaminase
B. Cystathionine synthase
C. Hypoxanthine guanine phosphoribosyltransferase
D. Phenylalanine hydroxylase
E. Xanthine oxidase

———————–

Want to know the ‘bottom line?’ Purchase a USMLE-Rx Subscription and get many more features, more questions, and passages from First Aid, including images, references, and other facts relevant to this question.

This practice question is an actual question from the USMLE-Rx Step 1 test bank. For more USMLE Step 1 prep, subscribe to our Flash Facts and Step 1 Express video series. Score the best deal on all three products with a Step 1 Triple Play Bundle.

USMLE-Rx Step 2 Qmax Challenge #21684

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Check out today’s Step 1 Qmax Question Challenge.

Know the answer? Post it below! Don’t forget to check back for an update with the correct answer and explanation (we’ll post it in the comments section below).

USMLE-Rx Step 2 Qmax Challenge #21684A 60-year-old white man presents to his primary care physician for an annual examination. He has a history of hypertension that is controlled with diet and medication. He has felt well. He has, however, noticed for the past 10 months a nonresolving small bump on his scalp that occasionally bleeds when he scratches it. He is a banker and does not spend much time outdoors, but had frequent sunburns as a boy. Examination reveals a 0.6-cm flesh-colored papule with telangiectatic vessels, a rolled edge, and slight central crusting located on his scalp (see image).

Which of the following is the expected progression of this lesion?

A. An initial radial growth phase that is followed by a vertical growth phase; prognosis is significantly related to depth of the lesion at time of excision
B. Good prognosis if excised early, but a propensity for lymphatogenous metastasis mandates frequent follow-up after excision
C. Occurs exclusively within the epidermis and has no malignant potential
D. Slow growth with destruction of local tissue that may extend along nerves to penetrate into the central nervous system
E. Will remain stable for an indefinite period, and is likely to regress with residual scarring if untreated

———————–

Want to know the ‘bottom line?’ Purchase a USMLE-Rx Subscription and get many more features, more questions, and passages from First Aid, including images, references, and other facts relevant to this question.

This practice question is an actual question from the USMLE-Rx Step 1 test bank. For more USMLE Step 1 prep, subscribe to our Flash Facts and Step 1 Express video series. Score the best deal on all three products with a Step 1 Triple Play Bundle.

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