USMLE-Rx Step 1 Practice Q's

USMLE-Rx Step 1 Qmax Challenge #3706

9

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USMLE-Rx Step 1 Qmax Challenge #3706A 52-year-old woman presents with new-onset jaundice. After extensive work-up, a liver biopsy is called for. The histologic section is shown in the image. The cells indicated by the arrows are most likely undergoing which of the following processes?

A. Apoptosis
B. Caseous necrosis
C. Coagulative necrosis
D. Fat necrosis
E. Liquefactive necrosis

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USMLE-Rx Step 1 Qmax Challenge #3702

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USMLE-Rx Step 1 Qmax Challenge #3702An electron micrograph of two adjacent cells is shown in the image.

Which of the following is the most likely function of the dark band-like structures at the center of the image?

A. To allow for passage of small molecules and electrolytes
B. To anchor the two adjacent cells
C. To prevent luminal contents from entering the intercellular space
D. To produce proteins that are destined to be secreted, to be included in the plasma membrane or lysosomes
E. To provide structural support and bind epithelium to underlying tissues

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USMLE-Rx Step 1 Qmax Challenge #3695

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USMLE-Rx Step 1 Qmax Challenge #3695Individual 5 in generation II and individual 3 in generation III have a similar condition (see image).

What is the most likely nature of their illness?

A. A deficiency of glucocerebrosidase
B. Damage to the chromosome 15, resulting in hyperphagia
C. Depression, dementia, and uncontrolled dance-like movements
D. Difficulty achieving hemostasis after wisdom tooth extraction
E. Hyperchloric apocrine gland secretion

———————–

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This practice question is an actual question from the USMLE-Rx Step 1 test bank. For more USMLE Step 1 prep, subscribe to our Flash Facts and Step 1 Express video series. Score the best deal on all three products with a Step 1 Triple Play Bundle.

USMLE-Rx Step 1 Qmax Challenge #3613

6

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USMLE-Rx Step 1 Qmax Challenge #3613A 57-year-old man presents to his internist because of abnormal bleeding following a routine dental cleaning. Over the past several months he has experienced symptoms of headache, dizziness, fatigue, decreased vision, and occasional epistaxis. He has also begun noticing “lumps” on his armpits and groin region. The spleen tip is palpable on physical examination. Laboratory tests show a hemoglobin level of 11 g/dL, blood urea nitrogen of 25 mg/dL, calcium of 9.1, and total protein of 15 g/dL. Immunofixation shows high levels of IgM. Results of bone marrow biopsy are shown in the image.

Which of the following is the most likely explanation for the patient’s symptoms?

A. Heavy-chain disease
B. Monoclonal gammopathy of undetermined significance
C. Multiple myeloma
D. Primary amyloidosis
E. Waldenström’s macroglobulinemia

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USMLE-Rx Step 1 Qmax Challenge #3590

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USMLE-Rx Step 1 Qmax Challenge #3590An exceptionally tall 35-year-old man with long fingers and a history of poor vision presents to the emergency department complaining of severe chest pain radiating to the middle of his back. The physicians believe that he is having a heart attack and treat him accordingly. Sadly, he dies during the resuscitation attempt, and it was later discovered that he had a different fatal complication as a result of a chronic illness. A microscope slide of his aorta is shown in the image.

What microscopic pathology is responsible for the complication that led to his death?

A. Atherosclerosis
B. Calcified aortic valve
C. Cystic medial necrosis
D. Mitral valve prolapse
E. Syphilitic aortitis

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USMLE-Rx Step 1 Qmax Challenge #3574

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USMLE-Rx Step 1 Qmax Challenge #3574A 68-year-old man suffers a stroke of his left posterior inferior cerebellar artery. One of the cell types damaged by the stroke is shown in the image.

What is the neurotransmitter used by this neuron subtype?

A. ?-Aminobutyric acid
B. Acetylcholine
C. Dopamine
D. Glutamate
E. Glycine
F. Norepinephrine

———————–

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This practice question is an actual question from the USMLE-Rx Step 1 test bank. For more USMLE Step 1 prep, subscribe to our Flash Facts and Step 1 Express video series. Score the best deal on all three products with a Step 1 Triple Play Bundle.

USMLE-Rx Step 1 Qmax Challenge #3567

7

Check out today’s Step 1 Qmax Question Challenge.

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USMLE-Rx Step 1 Qmax Challenge #3567A 37-year-old man complains of an unsteady gait when he walks. He has a history of drug abuse, alcohol abuse, and numerous sex partners. A myelin stain of the spinal cord is shown in the image.

Which of the following organisms is responsible for this spinal cord lesion?

A. Herpes simplex virus
B. HIV
C. Mycobacterium tuberculosis
D. Poliovirus
E. Treponema pallidum

———————–

Want to know the ‘bottom line?’ Purchase a USMLE-Rx Subscription and get many more features, more questions, and passages from First Aid, including images, references, and other facts relevant to this question.

This practice question is an actual question from the USMLE-Rx Step 1 test bank. For more USMLE Step 1 prep, subscribe to our Flash Facts and Step 1 Express video series. Score the best deal on all three products with a Step 1 Triple Play Bundle.

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